Monday, August 12, 2013

Lymphatic System

The Organ System

Lymphatic System

Fundamentals:

  • Type of circulatory system composed of one way vessels that become larger as they move toward the center of the body
  • Lies parallel to the systemic and pulmonary circulations
  • Collects excess fluid (about 4L/day) that leaks into the interstitial space and returns it to the vena cava

Anatomy:

  • Lymphatic Capillaries
    • Not all the fluid is reabsorbed in the interstitial space
    • Excess fluid is collected and then returned to cardiovascular circulation
  • Lacteals
    • Collects facts in the form of chylomycrons from the villi in the Small Intestine and deliver them to the Liver
  • Lymph Node/Vessels - filters out foreign particles that could potentially lead to disease
    • Contain immune cells(B Cells)
    • A place for antigens from microbes to interact with adaptive immune system for activation

Concept:

  • If this system was blocked, edema would follow
    • INC in interstitial fluid

Application:

  • Heart surgery pts have swollen legs and ankles, where the heart cannot pump the blood fast enough and the blood begins to back up
  • Gravity pulls the fluid toward lower extremities
Lymphatic fluid and venous system join to comprise a large thoracic duct in the chest Fluid should be checked for pathogens only before being returned to the systemic highway system

Terminology:

  • Lacteals: smallest lymphatic vessels