Monday, August 12, 2013

Arteries

Blood Vessels

Aorta, Arteries and Arterioles

Fundamentals:

  • Aorta is the largest artery
  • Strong and thick walls

Function:

  • Carry blood AWAY from the heart
    • Major area of resistance - Arterioles and have strong muscular walls
    • Meaning that the largest drop in BP occurs at the arterioles
      • WHY? Arteriole's hydrostatic pressure is relatively high

Anatomy:

  • Lumen
    • Lined with endothelial cells
  • Tunica intima
  • Tunica media
  • Tunica externa
  • Smooth muscle
  • Connective tissue
    • Collagenous fibers
    • Elastic fibers

Specifications/Fundamentals:

  • Total cross sectional area 5cm^2
  • Blood pressure 80-120 mmHg (average 100 mmHg)
  • Volume of blood 16-20%
  • Velocity 30 cm/s

Concept:

  • Blood Pressure Measurement
    • pressure that the baroreceptors are sensing as they monitor blood pressure"
    • Stethoscope on antecubital artery
    • Cuff inflated above arterial systolic pressure
    • Pressure of the cuff is decreased (manipulated using the turn nob at the pump)
    • The pressure below the systolic blood will jet through the artery
      • Turbulent flow because great pressure pushes through narrow area
      • Sound marks systolic
    • Pressure of the cuff is further decreased and the vessel regains original shape.
      • Turbulent flow becomes laminar flow
      • Change in sound marks diastolic pressure
  • Regulation
    • Autonomic Nervous System
      • Sympathetic - important in ANS
      • Parasympathetic
    • Hormonal regulation
    • Local tissue regulation
      • Metabolites circulate in the tissue and diffuse out to the blood vessels
      • Smooth muscle dialates to increase flow to particular area

Disorders/Diseases:

  • Atherosclerosis
    • Abrasion through pressure or substances allow choleserol/plaque to build up

Terminology:

  • Diastolic pressure - Heart
  • Systolic pressure - Heart
  • Blood Pressure: force/area of the body fluid exclusively in vessels
  • Baroreceptors - Heart
  • Endothelial cells: inside the cardiovascular system