Tuesday, August 13, 2013

Vibrio cholerae


Microbe Profile(1)

Comma bacillus

1-Charactersitics:

  • Pink cells
    • Comma shaped
  • Motile
    • Polar flagella
  • Oxidase pos
  • Alkalinic growth
  • Metabolism
    • SLOW LAC fermetnation
    • GLU fermentation

2-Location

  • Water environments

3-Virluence Factors

  • Motility - polar flagellum
  • Toxin Coregulated Pili
  • Adhesin
  • Bacterial cell surface
    • 2 Surface proteins that agglutinate RBCs
    • Hemagglutin do not appear to have major role in virulence
  • Mucinase
  • Choleragen - Cholera Toxin
  • O Antigen

-Diseases


Treatment

  • NONE! - self limiting - Antibiotics DO SHOTRTEN duration of illness
  • Fluid replacement

4-Information/History


5-Media/Identifcation:

  • MAC - colorless
  • TSI - yellow
  • Serotyping
  • Darkfield

Newsworthy Cases:

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