Snake Venom Poisoning
ConditionsDiseases List
Snake Venom Poisoning
Fundamentals:
- 50-60 proteins that vary from species to species
- Enzymes that digest cell membranes
- EX: Phospholipases
- Brake phospholipids and destroy phospholipids of skeletal muscles exposing insides of cells
- ER, mitochondria, nuc env membrane, plasma membrane all contain phospholipids
- Target the RBCs = hemolysis
- EX: Collagenases
- Digest collagen - connective tissue
- EX: hyaluronidase
- DIgest glycosaminoglycan - connective tissue
- Both destroy tissue at the site of the bite enabling the venom to spread more readily throughout the victim
- EX: Proteases
- Degrade basement membranes and components of extracellular matrix = severe tissue damage
- Stimulate formation of blood clotts as well as digest blood clots
- Neurotoxic activities
- Immobilize prey while the digestive enzymes take effect
Concepts:
Additional Information:
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