Tuesday, August 13, 2013

Periodic Acid Cleavage

Carbohydrates

Cleaves the vicinal diols of aldoses/ketoses

Attacks aldoses/ketoses

Periodic Acid Cleavage

  • Vicinal diol -(HIO4)-> Ketones & Aldehydes + HIO3 + H2O
  • Sugar -(Ex HIO4)-> [Sugar size-2]# of Formic acid & Formaldehyde from Carbonyl

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