IeCST

Signal Transduction

Phase of signal transduction that release of signals by a cell to the outside of the cell

Intercellular Signal Tranduction:

Types:

Adjacent Cell to Cell

• Juxtacrine

Secretion

• Endocrine
• Paracrine
• Synaptic
• Autocrine

Concepts:

• The shorter the distance the higher the concentrations, high Km, lower the affinity, shorter duration
• DEC Distance - DEC duration, DEC affinity, INC Km, INC conc, INC # tissue control
• Low distance (Autocrine, Synaptic/Juxtacrine, Paracrine, Endorine) High Distance

Additional Information:

• Wikipedia