Streptococcus pyogenes

• Interactive Microbiology Atlas - Back
• Differential Tests
  • Gram Stain - Gram Stain

(Unsorted: Hemolysis, Catalse, Bacitracin, STX, Precipitn, ASO titer, Anti DNAse titer, CAMP rxn, NaCl, Blie sculin)

• Taxonomy
  • Streptococeae - Family
    • Streptococcus - Genus

Microbe Profile(1)

1-Charactersitics:

• Purple cells
  • Coccic
    • Grouped in pairs / chains
• catalase - neg
• oxidase - neg
• Homofermentative
  • facultative anaerobes. Growth usually stimulated by CO2.
• Group A Strep:
  • Cell Wall Composition
    • 30% NAG
    • 60% NA-rhamnose
• Hemolytic (sheep rbcs)
• Bacitracin susceptibility (bacillus source)
• Hippurate hydrolysis ?
• Ninhydrin reagent – glycine
• Precipitated by ferrochloride
• CAMP
• Bile escalin - Growth in 6.5%NaCl

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2-Location

• Throat and Skin

3-Virluence Factors

• Beta Hemolysis
  • Protein O
• M Protein
• Capsule
• DNAse
  • A
  • B
  • C
  • D
• Hyalurondiase
• Protease/Peptidases/Proteinase
• NADase
• Streptokinase
• Erythrogenic toxin
• Lipoteichoic acid (LTA)

-Diseases

• Strep Throat
• Scarlet Fever
• Impetigo
• Bright's Disease
• Rheumatic Fever
• Necrotizing Fasciitis
• Streptococcal Toxic Shock Syndrome

Treatment

• ?

4-Information/History

• Wikipedia
• CDC
• Online Text - Todar
• Directors of Health Promotion and Education

Newsworthy Cases:

• Malyia: California