Synaptic Cleft
Neurons
Synaptic Clef/Synapse
Types of Receptors:
- Nicotinic ach
- Responds to nicotine as an agonist and curare as antagonist
- Nicotine: psychoactive alkaloid
- Toxic, places stress on the heart and entire CVS - HOW?
- PNS through the nicotinic receptors
- Since there is a "stress added to the heart"
- Additive
- Muscarinic ach
- Responds to muscarine as agonist and scopolamine as antagonist
UNSORTEDED
We don't want transmission to continue indefinitely so there must be a
way to remove the neurotransmitters from the synaptic cleft
Some are broken down by enzymatic reactions
Some use reuptake carriers
Some diffuse out of the area
Difference btwn electical and chemcial transmission
Neurons use both - allornothinc
Chemical molecuels are used to pass messages in a modulated manner
that depends on how much neutotransmitters is released
Inhibit acetylcholinesterase - elevating synaptic levels of
acetylcholine
====Terminology:====
Synapse: connection btwn two neurons
Most synapses are chemical in nature using neurotransmitters to send
messages
Presynaptic terminal/neuron: Terminal before the synapse
Postsynaptic terminal: Neuron receiving information through its
dendrites
Effector cell: signals sent by neurons that target a gland/muscle
Neutrotransmitters: small molecules that send the messeges from one
cell to the next
Sorted in membrane bound vessicles
Vessicles weight for AP to propagate down the axon and depolarize the
terminal membrane
